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Defective suppressor function in CD4(+)CD25(+) T-cells from patients with type 1 diabetes.
 
Diabetes OD > Diabetes Pathogenesis > T1DM > Autoimmunity > Defects in Self-Tolerance > Loss of Suppression Activity > Treg Cells > Journal Article

(Journal Article): Defective suppressor function in CD4(+)CD25(+) T-cells from patients with type 1 diabetes.
 
Lindley S, Dayan CM, Bishop A, Roep BO, Peakman M, Tree TI
 
IN: Diabetes 2005; 54:92-99
Impact Factor(s) of Diabetes: 8.848 (2004), 8.298 (2003), 8.256 (2002), 7.7 (2001)

ABSTRACT: Type 1 diabetes is a T-cell-mediated disease that is associated with loss of immunological tolerance to self-antigens. The mechanisms involved in maintenance of peripheral toleranc... Click HERE for details