In Vitro Derivation and Differentiation of Human ESC

Sub-Areas to In Vitro Derivation and Differentiation of Human ESC:

Growth Factors (1)


(Journal Article): Embryonic stem cell lines from human blastocysts: somatic differentiation in vitro.
 
Reubinoff BE, Pera MF, Fong CY, Trounson A, Bongso A
 
IN: Nat Biotech 2000; 18(4):399-404

ABSTRACT: We describe the derivation of pluripotent embryonic stem (ES) cells from human blastocysts. Two diploid ES cell lines have been cultivated in vitro for extended periods while maint... Click HERE for details

 

(Journal Article): Derivation of pluripotent stem cells from cultured human primordial germ cells.
 
Shamblott MJ, Axelman J, Wang S, Bugg EM, Littlefield JW, Donovan PJ, Blumenthal PD, Huggins GR, Gearhart JD
 
IN: Proc Natl Acad Sci U S A 1998; 95(23):13726-13731
Impact Factor(s) of Proc Natl Acad Sci U S A: 10.452 (2004), 10.272 (2003), 10.7 (2002), 10.896 (2001)

ABSTRACT: Human pluripotent stem cells would be invaluable for in vitro studies of aspects of human embryogenesis. With the goal of establishing pluripotent stem cell lines, gonadal ridges a... Click HERE for details

 

(Journal Article): Human embryonic germ cell derivatives express a broad range of developmentally distinct markers and proliferate extensively in vitro.
 
Shamblott MJ, Axelman J, Littlefield JW, Blumenthal PD, Huggins GR, Cui Y, Cheng L, Gearhart JD
 
IN: Proc Natl Acad Sci U S A 2001; 98(1):113-118
Impact Factor(s) of Proc Natl Acad Sci U S A: 10.452 (2004), 10.272 (2003), 10.7 (2002), 10.896 (2001)

ABSTRACT: Human pluripotent stem cells (hPSCs) have been derived from the inner cell mass cells of blastocysts (embryonic stem cells) and primordial germ cells of the developing gonadal ridg... Click HERE for details

 

(Journal Article): In vitro differentiation of embryonic stem cells.
 
Keller GM
 
IN: Curr Opin Cell Biol 1995; 7(6):862-869
Impact Factor(s) of Curr Opin Cell Biol: 15.422 (2004), 18.176 (2003), 19.022 (2002), 21.568 (2001)

ABSTRACT: Under appropriate conditions in culture, embryonic stem cells will differentiate and form embryoid bodies that have been shown to contain cells of the hematopoietic, endothelial, m... Click HERE for details

 

(Journal Article): Differentiation of human embryonic stem cells into embryoid bodies compromising the three embryonic germ layers.
 
Itskovitz-Eldor J, Schuldiner M, Karsenti D, Eden A, Yanuka O, Amit M, Soreq H, Benvenisty N
 
IN: Mol Med 2000; 6(2):88-95
Impact Factor(s) of Mol Med: 3.576 (2004), 2.656 (2003), 3.234 (2001)

ABSTRACT: BACKGROUND: Embryonic stem (ES) cells are lines of cells that are isolated from blastocysts. The murine ES cells were demonstrated to be true pluripotent cells as they differentiat... Click HERE for details

 

(Journal Article): Clonally derived human embryonic stem cell lines maintain pluripotency and proliferative potential for prolonged periods of culture.
 
Amit M, Carpenter MK, Inokuma MS, Chiu CP, Harris CP, Waknitz MA, Itskovitz-Eldor J, Thomson JA
 
IN: Dev Biol 2000; 227(2):271-278
Impact Factor(s) of Dev Biol: 5.432 (2004), 5.351 (2003), 5.194 (2002), 5.558 (2001)

ABSTRACT: Embryonic stem (ES) cell lines derived from human blastocysts have the developmental potential to form derivatives of all three embryonic germ layers even after prolonged culture. ... Click HERE for details

 

(Journal Article): Insulin production by human embyronic stem cells.
 
Assady S, Maor G, Amit M, Itskovitz-Eldor J, Skorecki KL
 
IN: Diabetes 2001; 50(8):1-7
Impact Factor(s) of Diabetes: 8.848 (2004), 8.298 (2003), 8.256 (2002), 7.7 (2001)

ABSTRACT: Type 1 diabetes generally results from autoimmune destruction of pancreatic islet beta-cells, with consequent absolute insulin deficiency and complete dependence on exogenous insul... Click HERE for details

 



 
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