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Pancreatic and duodenal homeobox gene 1 induces expression of insulin genes in liver and ameliorates streptozotocin-induced hyperglycemia.
 
Diabetes OD > Reversal/Prevention of Diabetes > Gene Therapy > Insulin-Production by Non-Islet Tissue > Recombinant-adenovirus-mediated gene transfer of PDX-1 > Journal Article

(Journal Article): Pancreatic and duodenal homeobox gene 1 induces expression of insulin genes in liver and ameliorates streptozotocin-induced hyperglycemia.
 
Ferber S, Halkin A, Cohen H, Ber I, Einav Y, Goldberg I, Barshack I, Seijffers R, Kopolovic J, Kaiser N, Karasik A
 
IN: Nat Med 2000; 6(6):568-572
Impact Factor(s) of Nat Med: 28.878 (2005), 31.223 (2004), 30.55 (2003), 28.74 (2002), 27.906 (2001)

ABSTRACT: Insulin gene expression is restricted to islet beta cells of the mammalian pancreas through specific control mechanisms mediated in part by specific transcription factors. The prot... Click HERE for details