Dominant negative MyD88 proteins inhibit interleukin-1beta /interferon-gamma-mediated induction of nuclear factor kappa B-dependent nitrite production and apoptosis in beta cells.

(Journal Article): Dominant negative MyD88 proteins inhibit interleukin-1beta /interferon-gamma-mediated induction of nuclear factor kappa B-dependent nitrite production and apoptosis in beta cells.

Dupraz P, Cottet S, Hamburger F, Dolci W, Felley-Bosco E, Thorens B

IN: J Biol Chem 2000; 275(48):37672–37678.-
Impact Factor(s) of J Biol Chem: 6.355 (2004), 6.482 (2003), 7.258 (2001)

ABSTRACT: Insulin-dependent diabetes mellitus is an autoimmune disease in which pancreatic islet beta cells are destroyed by a combination of immunological and inflammatory mechanisms. In pa... Click HERE for details