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Oral Tolerization
Sub-Areas to Oral Tolerization:
TGF-beta-secretion
(1)
(Journal Article): Antigen-specific TGF-beta1 secretion with bovine myelin oral tolerization in multiple sclerosis.
Fukaura H, Kent SC, Pietrusewicz MJ, Khoury SJ, Weiner HL, Hafler DA
IN:
Ann N Y Acad Sci
1996; 778:251-257
Impact Factor(s) of Ann N Y Acad Sci: 1.789 (2004), 1.892 (2003), 1.682 (2002), 1.593 (2001)
ABSTRACT:
Multiple sclerosis is a presumed autoimmune disease, associated with inflammation in the CNS white matter, mediated by autoreactive T cells. We previously reported that oral myelin...
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(Journal Article): Oral administration of myelin induces antigen-specific TGF-beta 1 secreting T cells in patients with multiple sclerosis.
Hafler DA, Kent SC, Pietrusewicz MJ, Khoury SJ, Weiner HL, Fukaura H
IN:
Ann N Y Acad Sci
1997; 835:120-131
Impact Factor(s) of Ann N Y Acad Sci: 1.789 (2004), 1.892 (2003), 1.682 (2002), 1.593 (2001)
ABSTRACT:
Oral administration of antigen is a long-recognized method of inducing systemic immune tolerance. In animals with experimental autoimmune disease, a major mechanism of oral toleran...
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(Journal Article): Regulatory T cell clones induced by oral tolerance: suppression of autoimmune encephalomyelitis.
Chen Y, Kuchroo VK, Inobe J, Hafler DA, Weiner HL
IN:
Science
1994; 265(5176):1237-1240
Impact Factor(s) of Science: 30.927 (2005), 31.853 (2004), 29.162 (2003), 26.682 (2002), 23.329 (2001)
ABSTRACT:
Experimental autoimmune encephalomyelitis (EAE) is a cell-mediated autoimmune disease that serves as an animal model for multiple sclerosis. Oral administration of myelin basic pro...
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