Sub-Areas to Treg cells:
T Cell Suppression
(2)
T Cell Homeostasis
(1)
Costimulation
(0)
Ag-derived
(1)
DC-induced
(1)
Virus-induced
(1)
FoxP3
(3)
TGF-beta-secretion
(3)
TNF-alpha
(1)
(Journal Article): Foxp3 programs the development and function of CD4+CD25+ regulatory T cells.
Fontenot JD, Gavin MA, Rudensky AY
IN:
Nat Immunol
2003; 4(4):330-336
ABSTRACT: CD4+CD25+ regulatory T cells are essential for the active suppression of autoimmunity. Here we report that the forkhead transcription factor Foxp3 is specifically expressed in CD4+... Click HERE for details
(Journal Article): A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis.
Groux H, O'Garra A, Bigler M, Rouleau M, Antonenko S, de Vries JE, Roncarolo MG
IN:
Nature
1997; 389(6652):737-742
ABSTRACT: Induction and maintenance of peripheral tolerance are important mechanisms to maintain the balance of the immune system. In addition to the deletion of T cells and their failure to... Click HERE for details
(Journal Article): The infusion of ex vivo activated and expanded CD4(+)CD25(+) immune regulatory cells inhibits graft-versus-host disease lethality.
Taylor PA, Lees CJ, Blazar BR
IN:
Blood
2002; 99(10):3493-3499
ABSTRACT: Immune regulatory CD4(+)CD25(+) cells play a vital role in the induction and maintenance of self-tolerance and the prevention of autoimmunity. Recently, CD4(+)CD25(+) cells have be... Click HERE for details
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