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(Journal Article): Mechanism of disease: glucose transporters and insulin action: implication for insulin resistance and diabetes mellitus.
Shepherd PR, Kahn BB
IN:
N Engl J Med
1999; 341(4):248-257
Impact Factor(s) of N Engl J Med: 44.016 (2005), 38.57 (2004), 34.833 (2003), 29.065 (2001)
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ABSTRACT: Insulin was discovered more than 75 years ago, but only recently have we begun to understand the mechanisms by which insulin promotes the uptake of glucose into cells. This review discusses recent advances, their contribution to our understanding of the pathogenesis of diabetes mellitus, and their implications for the design of new therapies to prevent and treat diabetes and its complications.
TYPE OF PUBLICATION: Review
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