(Journal Article): Anaplastic Pancreatic Carcinoma. A Case Report and Review of Literature
 
Chadha MK, LeVea C, Javle M, Kuvshinoff B, Vijaykumar R, Iyer R (Departments of Medicine, Pathology, Surgery and Radiology, Roswell Park Cancer Institute. Buffalo, NY, USA, milind.javle@roswellpark.org )
 
IN: JOP. J Pancreas (Online) 2004; 05(6):512-515

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ABSTRACT: CONTEXT: Anaplastic pancreatic carcinoma is an aggressive neoplasm with survival measurable in weeks. It presents as a large cystic mass with loco-regional and distant spread. Three histological types have been described: pleomorphic, spindle cell and sarcomatoid. CASE REPORT: We describe the case of a 74-year-old woman with pleomorphic anaplastic carcinoma of the pancreas diagnosed after laparoscopic biopsy. The patient had a rapid downhill course with progression of the disease and demise within 4 weeks after diagnostic laparoscopy. CONCLUSION: Due to the rapid spread of the disease, no effective cure exists for these tumors. A brief review of the histological and radiological findings and the possible mechanisms of the pathogenesis of anaplastic tumors is included in the discussion.

TYPE OF PUBLICATION: Case Report